Thursday Common Hour and Faculty Research Committee (FRC) Lecture Series: Quick, Small, and Complicated - Meeting the Challenges of Single Cell Measurements of Stress Responses by Michelle L. Kovarik

Thursday, November 30, 2017
12:15 PM - 1:20 PM
Hallden Hall - North Wing Dangremond Family Commons 104
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Ellen Hart
Dean of Faculty

Michelle L. Kovarik, Assistant Professor of Chemistry

Cells experience a wide range of stressful situations, including nutrient deprivation and exposure to reactive oxygen species. Interestingly, these stressful situations evoke a wide range of responses in individual cells. This heterogeneity in stress responses may be adaptive since a population of genetically identical cells is able to test a range of responses. To study this phenomenon, we must measure individual living cells, which are limited in volume, contain complex biochemical mixtures, and respond dynamically to their environment. These challenges frame interesting analytical problems that we are addressing using molecular tools and microfluidic technology.

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